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KMID : 1156220160420010010
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Journal of Environmental Health Sciences
2016 Volume.42 No. 1 p.10 ~ p.18
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Accumulation of Microcystins in Fish and Evaluation of Potential Human Health Risks: A Case Study on a Eutrophic Reservoir in Korea
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윤효정:Yoon Hyo-Jung
서정관:Seo Jung-Kwan/김탁수:Kim Tak-Soo/조아름:Jo A-Reum/김정곤:Kim Jung-Kon/이두희:Lee Doo-Hee/김필제:Kim Pil-Je/최경희:Choi Kyung-Hee
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Abstract
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Objectives: Microcystin (MC) produced during cyanobacterial blooms is a worldwide problem presenting a serious health threats to humans and ecosystems. During July through October of 2013, the Ilwol Reservoir experienced a high biomass of phytoplankton (maximum 211.7 mg/m3 of Chlorophyll-a) containing the toxigenic cyanobacterium Oscillatoria sp. The aim of this study is to analyze MC concentration in the reservoir water, as well as in representative fish species (Carassius cuvieri, Carassius auratus, Channa argus). We also evaluated the human health risk of exposure to MCs accumulated in the fish.
Methods: Concentrations of MCs in the water and fish samples were analyzed by liquid chromatography with a triple quadrupole tandem mass spectrometer (LC/MS/MS) and enzyme-linked immunosorbent assay (ELISA).
Results: The total levels of four MC variants, including MC-LR, MC-RR, MC-YR and MC-LA were below the WHO drinking water guideline limit (1 ug MC-LR per liter) both for the dissolved and particulate fraction present in the water samples. The mean MC concentrations in the livers of all species were significantly higher than in the gills (p < 0.01) and muscles (p < 0.05). The values of estimated daily intake of MCs in muscles, the edible part of the fish, would be only 0.005?0.015 μg/kg·day, much lower than WHO’s provisional tolerable daily intake of 0.04 μg/kg·day.
Conclusion: This study suggests that, owing to the spatial distribution or temporal variation of MC, there is a need for careful monitoring of cyanotoxin in reservoir water and aquatic animals to protect public health.
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KEYWORD
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Accumulation, cyanobacterial bloom, health risks, microcystin
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